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細(xì)胞分裂周期因子7(CDC7)重組蛋白 真核細(xì)胞中的DNA復(fù)制依賴于復(fù)制起點(diǎn)處復(fù)制前復(fù)合物(preRC)的磷酸化。兩種蛋白質(zhì)復(fù)合物介導(dǎo)了這一事件,即細(xì)胞周期蛋白依賴性激酶(CDK)復(fù)合物和Cdc7激酶ASK復(fù)合物。Cdc7激酶的活性在細(xì)胞周期中振蕩。Cdc7激酶的主要靶點(diǎn)是屬于MCM復(fù)合物的蛋白質(zhì)(迷你染色體維持蛋白)。Cdc7激酶在減數(shù)分裂、檢查點(diǎn)反應(yīng)、染色體結(jié)構(gòu)的維持和修復(fù)中也很重要。
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品牌 | 信裕生物 | CAS | 詳見說明書 |
---|---|---|---|
分子式 | 詳見說明書 | 純度 | > 95% |
分子量 | 21.2kDa | 貨號(hào) | XY91436RPHu01 |
規(guī)格 | 50µg/100µg | 供貨周期 | 一周 |
主要用途 | SDS-PAGE; WB | 應(yīng)用領(lǐng)域 | 生物產(chǎn)業(yè) |
Recombinant Cell Division Cycle Protein 7 (CDC7)
細(xì)胞分裂周期因子7(CDC7)重組蛋白
[ PROPERTIES ]
Source:Prokaryotic expression
Host: E.coli
Residues:Glu2~Thr232
Tags:N-terminal His Tag
Subcellular Location: Nucleus
Purity: > 95%
Traits:Freeze-dried powder
Buffer formulation: BS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Original Concentration:200µg/mL
Applications:Positive Control; Immunogen; SDS-PAGE; WB.
(May be suitable for use in other assays to be determined by the end user.)
Predicted isoelectric point:8.4
Predicted Molecular Mass:30.1kDa
Accurate Molecular Mass:31kDa as determined by SDS-PAGE reducing conditions.
[ USAGE ]
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
[ STORAGE AND STABILITY ]
Storage: Avoid repeated freeze/thaw cycles.
Store at 2-8oC for one month.
Aliquot and store at -80oC for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
[SEQUENCE ]
[ IDENTIFICATION ]
[ IMPORTANT NOTE ]
The kit is designed for research use only, we will not be responsible for any issue if the kit was used in clinical diagnostic or any other procedures.
特別提示:本公司的所有產(chǎn)品僅可用于科研實(shí)驗(yàn),嚴(yán)禁用于臨床醫(yī)療及其他非科研用途!以實(shí)際收貨產(chǎn)品說明書為準(zhǔn),網(wǎng)站說明書僅供參考!
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